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Table 3 Properties and applications of important natural polymers used to ensure stabilization of MIONPs

From: Multifunctional magnetic iron oxide nanoparticles: diverse synthetic approaches, surface modifications, cytotoxicity towards biomedical and industrial applications

NameNature and sourceCharacteristicsApplications
AlginateAnionic polymer obtained from brown seaweedBiocompatible
Low cost and less toxicity
Addition of divalent cations result in mild gelation leads to biomedical applications
Used in
Delivery of low molecular weight drugs and proteins
Wound dressing
Tissue and bone regeneration
Transplantation of stem cells
ChitosanCationic linear polymer derived from partial deacetylation of chitinBiocompatible and biodegradable
Low allergenicity
Non-viral gene delivery system
Obesity and age-related disease treatment
Wound healing
Dry mouth syndrome treatment
Water treatment
DextranWater-soluble polysaccharide consists of mainly α-1,6-glycosides and rarely with α-1,3 branches obtained from bacteriaBiocompatible and biodegradable
Optimum polar interactions
Low cost and simple alternation
Colloidal solution is get stabilized by dextran and also helps in increasing circulation time in blood
PullulanWater-soluble polysaccharide comprising of linear chains of d-glycopyranosyl units from fungus Aureobasidium pullulansAdhesive ability
Boost nanoparticle colloidal stability
Accelerated biocompatibility
Targeted drug delivery along with excellent cytotoxic outcome
Transmucosal protein delivery