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Table 4 Structure, properties and applications of important synthetic polymers used to stabilize MIONPs

From: Multifunctional magnetic iron oxide nanoparticles: diverse synthetic approaches, surface modifications, cytotoxicity towards biomedical and industrial applications

NameStructureCharacteristics and applications
Polyethylene glycol (PEG) Surface shielding
Boost blood circulation
Solubility in buffer
Decrease charge-based interactions
Polyvinyl alcohol (PVA) Backbone chain of carbon with hydroxyl group strengthen the hydrophilic and dispersion capacity in bio fluids
Prevent nanoparticle self-aggregation
Polyethyleneimine (PEI) Non toxicity results in efficient gene delivery system
Branched PEI consists of primary, secondary and tertiary amino group results in transfection applications attributed by its high buffering capacity
Polyacrylic acid (PAA) Cell viability and high stability
Non-aggregated dispersed state makes excellent protectant in drug delivery systems especially for ophthalmic and buccal
Poly(methyl methacrylate) (PMMA) Hindrance towards chemical hydrolysis
Flexible and biocompatible
Entangle hydrophobic drugs
Poly(alkyl cyanoacrylate) (PACC) Biodegradable
Easy preparation of nanoparticles in aqueous media
Targeted drug delivery in brain by diffuse across tumour cell membrane